WatchProSite moderator Patrick_y has confirmed the advertisement as a genuine Patek Philippe advertisement in genuine FORTUNE magazines. FORTUNE magazine has a circulation numbering around 850,000 in print and digital print versions.

Another member has already mentioned the "look after it" (traditional Patek Philippe verbiage) and "take care of it" verbiage difference.
And usually, a Patek Philippe advertisement will include a model number. This one does not. However, there have been Patek Philippe advertisements in the more distant past that did not always include model numbers.

Perhaps it'll be like the Banksy painting that got shredded...

Banksy's "Girl With Balloon" had a metamorphosis and turned into "Love Is In The Bin." This elaborate stunt created a significant uproar in the art community at first, and later the art community found acceptance in the artist's work. In the end, the "interactive artwork" resulted in tremendous exposure for the artist. Solidifying his name to be remembered for decades to come.
What does Patek Philippe have to gain from this hoax? Not much, a lot of press, but this would be very atypical guerrilla marketing for a luxury brand - such a stunt would even be considered "beneath the brand" to do such a thing. But, the world is changing, and this may be considered an acceptable idea in the future. Would Patek Philippe do something so highly unusual? Or would Patek Philippe design such a bizarre looking watch?
As mentioned earlier, FORTUNE magazine has a circulation of around 850,000 subscribers for both print and digital print subscription. It is unclear how many have seen this advertisement, but it is a substantial amount of people. Would Patek Philippe play such a hoax? We shall find out, the watch launches in about 5 days or 120 hours. Cast your votes now!
Looking forward to reading your thoughts!
Moderator Edit: We have confirmation from Patek Philippe that renders this posting obsolete and we are locking the thread. Thank you for your participation.