If the watch is consistently fast or slow you can have it regulated. If its performance changes by that much, it's probably the result of either (1) positional variation that is much greater than should exist; or (2) the watch's being thrown off by movement when you are wearing it, which also should not really happen to that extent. The variation wouldn't be unacceptable in a cheap watch, but a Vacheron should perform better. Chances are that the problem is primarily one of lubrication, indication that servicing might be in order.