Any watch runs at slightly different "speeds" in the six possible positions: dial up/down, crown left/right/up/down. This has been known for centuries, and certainly before Mr. Wilsdorf's grandparents were born. This is one of the basic errors that Breguet wanted to fix with the tourbillon, as the difference between horizontal and vertical in a pocketwatch of the period could be huge.
Adjusting a watch means tweaking the balance assembly to even the errors
out over as many positions as possible or to "put the errors" into little-used positions (John can give infinitely more
expert info here).
The difference in rate in the different positions can be used to correct errors over a 24-hour period by
leaving it in the appropriate position overnight to compensate for the
day's accumulated errors. Which leads to my favourite watch accuracy anomaly: a watch that gains 8 seconds in 16 hours when worn then loses 8 seconds in 8 hours on the bedside table has a rate of +/-0s over a 24-hour period - a seriously accurate watch!! 
nick