Andrew:
1 piece of evidence
My favourite watch, my father's 60's SS square Cal562 has the signed acrylic. The crystal is original and has has had many, many scratches polished out. I only noticed the symbol a few weeks ago, when inspecting some crazing. It was only visible (and I've looked for it before) under a blazing hot summer sun...
And yes. Hesalite is just a form of Acrylic. My guess is that it's etched. I am not sure you could get such sharp edges on acrylic if it was moulded-in. Alternatively, is might also be pressed into the crystal after moulding (cookie cutter style)