...with my and my family's cars it's never been a question. You like or need the car...and the number of doors is secondary. So it's always been a mix.
Alfas? Giulietta Spider and Guilia Super
BMW? E21 323, 2500 and E23 733
Jaguar? Only 4 doors. Series 1 XJ6s
VW? Mk1 GTI and B1 Passat Wagon
Riley? RMB and RMD DHC.
But thinking about it some more...most of the cars have been 4 door - too many more to list - much more practical when you have dogs.